- Mouse monoclonal [TNFA/1172] to TNF alpha
- Suitable for: IHC-P, ICC
- Reacts with: Rat, Human
- Isotype: IgM
- Immunogen: Recombinant full length protein corresponding to Human TNF alpha.
- Positive control: Human Erdheim Chester disease, rat stomach and rat pancreas tissues; ICC: HepG2 cells.
- pH: 7.2
- Preservative: 0.05% Sodium azide
- Constituents: 0.05% BSA, PBS
- Concentration: 100 µg at 0.2 mg/ml
- Purity: Protein A/G purified
- Light chain type: kappa
- Function:
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
Anti-TNF alpha antibody [TNFA/1172] | ABCAM | ab220210
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